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Leucine-rich repeat kinase 2 and alpha-synuclein: intersecting pathways in the pathogenesis of Parkinson's disease?

Although Parkinson's disease (PD) is generally a sporadic neurological disorder, the discovery of monogenic, hereditable forms of the disease has been crucial in delineating the molecular pathways that lead to this pathology. Genes responsible for familial PD can be ascribed to two categories b...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Greggio, Elisa, Bisaglia, Marco, Civiero, Laura, Bubacco, Luigi
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3035023/
https://ncbi.nlm.nih.gov/pubmed/21244648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-6-6
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