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Parkinson’s disease and immune system: is the culprit LRRKing in the periphery?

Leucine-rich repeat kinase 2 (LRRK2) is a large multidomain kinase/GTPase that has been recently linked to three pathological conditions: Parkinson’s disease; Crohn’s disease; and leprosy. Although LRRK2 physiological function is poorly understood, a potential role in inflammatory response is sugges...

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Detalhes bibliográficos
Main Authors: Greggio, Elisa, Civiero, Laura, Bisaglia, Marco, Bubacco, Luigi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3391996/
https://ncbi.nlm.nih.gov/pubmed/22594666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-9-94
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