ロード中...
The G2019S Pathogenic Mutation Disrupts Sensitivity of Leucine-Rich Repeat Kinase 2 to Manganese Kinase Inhibition
Mutations in leucine-repeat rich kinase-2 (LRRK2) are the most common cause of late-onset Parkinson disease. Previously, we showed that the G2019S pathogenic mutation can cause a dramatic increase (~10 fold) in kinase activity, far above other published studies. A notable experimental difference was...
保存先:
| 主要な著者: | , |
|---|---|
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2010
|
| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2963190/ https://ncbi.nlm.nih.gov/pubmed/20626563 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2010.06894.x |
| タグ: |
タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!
|