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Leucine-rich Repeat Kinase 2 Expression Leads to Aggresome Formation that is not Associated with α-Synuclein Inclusions
Mutations in leucine-rich repeat kinase-2 (LRRK2) are the most common known cause of Parkinson disease (PD), but how this protein results in the pathobiology of PD is unknown. Moreover, there is variability in pathology among cases and α-synuclein (α-syn) neuronal inclusions are often present but wh...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2722758/ https://ncbi.nlm.nih.gov/pubmed/19535993 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/NEN.0b013e3181aaf4fd |
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