cIAP1 and TAK1 protect cells from TNF-induced necrosis by preventing RIP1/RIP3-dependent reactive oxygen species production

Three members of the IAP family (X-linked inhibitor of apoptosis (XIAP), cellular inhibitor of apoptosis proteins-1/-2 (cIAP1 and cIAP2)) are potent suppressors of apoptosis. Recent studies have shown that cIAP1 and cIAP2, unlike XIAP, are not direct caspase inhibitors, but block apoptosis by functi...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Vanlangenakker, N, Vanden Berghe, T, Bogaert, P, Laukens, B, Zobel, K, Deshayes, K, Vucic, D, Fulda, S, Vandenabeele, P, Bertrand, M J M
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2011
Pynciau:
Original Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3131911/
https://ncbi.nlm.nih.gov/pubmed/21052097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2010.138
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