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TNF-induced necroptosis in L929 cells is tightly regulated by multiple TNFR1 complex I and II members

TNF receptor 1 signaling induces NF-κB activation and necroptosis in L929 cells. We previously reported that cellular inhibitor of apoptosis protein-mediated receptor-interacting protein 1 (RIP1) ubiquitination acts as a cytoprotective mechanism, whereas knockdown of cylindromatosis, a RIP1-deubiqui...

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Detalhes bibliográficos
Main Authors: Vanlangenakker, N, Bertrand, M J M, Bogaert, P, Vandenabeele, P, Vanden Berghe, T
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3223695/
https://ncbi.nlm.nih.gov/pubmed/22089168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2011.111
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