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Endoplasmic reticulum stress induces ligand-independent TNFR1-mediated necroptosis in L929 cells

Endoplasmic reticulum (ER) stress-induced cellular dysfunction and death is associated with several human diseases. It has been widely reported that ER stress kills through activation of the intrinsic mitochondrial apoptotic pathway. Here we demonstrate that ER stress can also induce necroptosis, an...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Saveljeva, S, Mc Laughlin, S L, Vandenabeele, P, Samali, A, Bertrand, M J M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4669746/
https://ncbi.nlm.nih.gov/pubmed/25569104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.548
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