Endoplasmic reticulum stress-mediated induction of SESTRIN 2 potentiates cell survival

Upregulation of SESTRIN 2 (SESN2) has been reported in response to diverse cellular stresses. In this study we demonstrate SESTRIN 2 induction following endoplasmic reticulum (ER) stress. ER stress-induced increases in SESTRIN 2 expression were dependent on both PERK and IRE1/XBP1 arms of the unfold...

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Udgivet i:Oncotarget
Main Authors: Saveljeva, Svetlana, Cleary, Patricia, Mnich, Katarzyna, Ayo, Abiodun, Pakos-Zebrucka, Karolina, Patterson, John B, Logue, Susan E., Samali, Afshin
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Research Paper: Autophagy and Cell Death
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4914282/
https://ncbi.nlm.nih.gov/pubmed/26930721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7601
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