Deficiency in the mitochondrial apoptotic pathway reveals the toxic potential of autophagy under ER stress conditions

Endoplasmic reticulum (ER) stress-induced cell death is normally associated with activation of the mitochondrial apoptotic pathway, which is characterized by CYCS (cytochrome c, somatic) release, apoptosome formation, and caspase activation, resulting in cell death. In this study, we demonstrate tha...

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Spremljeno u:
Bibliografski detalji
Izdano u:Autophagy
Glavni autori: Deegan, Shane, Saveljeva, Svetlana, Logue, Susan E, Pakos-Zebrucka, Karolina, Gupta, Sanjeev, Vandenabeele, Peter, Bertrand, Mathieu JM, Samali, Afshin
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2014
Teme:
Basic Research Papers
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4502706/
https://ncbi.nlm.nih.gov/pubmed/25470234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15548627.2014.981790
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