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Methods for Monitoring Endoplasmic Reticulum Stress and the Unfolded Protein Response

The endoplasmic reticulum (ER) is the site of folding of membrane and secreted proteins in the cell. Physiological or pathological processes that disturb protein folding in the endoplasmic reticulum cause ER stress and activate a set of signaling pathways termed the Unfolded Protein Response (UPR)....

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Detalhes bibliográficos
Main Authors: Samali, Afshin, FitzGerald, Una, Deegan, Shane, Gupta, Sanjeev
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2821749/
https://ncbi.nlm.nih.gov/pubmed/20169136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2010/830307
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