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Endoplasmic Reticulum Stress and Unfolded Protein Response in Neurodegenerative Diseases
The endoplasmic reticulum (ER) is an important organelle involved in protein quality control and cellular homeostasis. The accumulation of unfolded proteins leads to an ER stress, followed by an adaptive response via the activation of the unfolded protein response (UPR), PKR-like ER kinase (PERK), i...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
MDPI AG
2020-08-01
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Colecção: | International Journal of Molecular Sciences |
Assuntos: | |
Acesso em linha: | https://www.mdpi.com/1422-0067/21/17/6127 |
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