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Endoplasmic Reticulum Stress and Unfolded Protein Response in Neurodegenerative Diseases

The endoplasmic reticulum (ER) is an important organelle involved in protein quality control and cellular homeostasis. The accumulation of unfolded proteins leads to an ER stress, followed by an adaptive response via the activation of the unfolded protein response (UPR), PKR-like ER kinase (PERK), i...

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Detalhes bibliográficos
Main Authors: Rose Ghemrawi, Mostafa Khair
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2020-08-01
Colecção:International Journal of Molecular Sciences
Assuntos:
Acesso em linha:https://www.mdpi.com/1422-0067/21/17/6127
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