Endoplasmic Reticulum (ER) Stress and Unfolded Protein Response (UPR) in Mammalian Oocyte Maturation and Preimplantation Embryo Development

Mammalian oocytes and early embryos derived from in vitro production are highly susceptible to a variety of cellular stresses. During oocyte maturation and preimplantation embryo development, functional proteins must be folded properly in the endoplasmic reticulum (ER) to maintain oocyte and embryo...

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Main Authors: Tao Lin, Jae Eun Lee, Jung Won Kang, Hyeon Yeong Shin, Ju Bin Lee, Dong Il Jin
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2019-01-01
Colecção:International Journal of Molecular Sciences
Assuntos:
endoplasmic reticulum stress
unfolded protein response
oocytes
embryos
apoptosis
Acesso em linha:http://www.mdpi.com/1422-0067/20/2/409
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