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Endoplasmic Reticulum Stress Sensing in the Unfolded Protein Response

Secretory and transmembrane proteins enter the endoplasmic reticulum (ER) as unfolded proteins and exit as either folded proteins in transit to their target organelles or as misfolded proteins targeted for degradation. The unfolded protein response (UPR) maintains the protein-folding homeostasis wit...

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Main Authors: Gardner, Brooke M., Pincus, David, Gotthardt, Katja, Gallagher, Ciara M., Walter, Peter
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3578356/
https://ncbi.nlm.nih.gov/pubmed/23388626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a013169
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