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Endoplasmic Reticulum Stress Sensing in the Unfolded Protein Response
Secretory and transmembrane proteins enter the endoplasmic reticulum (ER) as unfolded proteins and exit as either folded proteins in transit to their target organelles or as misfolded proteins targeted for degradation. The unfolded protein response (UPR) maintains the protein-folding homeostasis wit...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3578356/ https://ncbi.nlm.nih.gov/pubmed/23388626 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a013169 |
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