Local delivery of rapamycin: a toxicity and efficacy study in an experimental malignant glioma model in rats

Rapamycin, an anti-proliferative agent, is effective in the treatment of renal cell carcinoma and recurrent breast cancers. We proposed that this potent mammalian target of rapamycin inhibitor may be useful for the treatment of gliomas as well. We examined the cytotoxicity of rapamycin against a rod...

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Dettagli Bibliografici
Autori principali: Tyler, Betty, Wadsworth, Scott, Recinos, Violette, Mehta, Vivek, Vellimana, Ananth, Li, Khan, Rosenblatt, Joel, Do, Hiep, Gallia, Gary L., Siu, I-Mei, Wicks, Robert T., Rudek, Michelle A., Zhao, Ming, Brem, Henry
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2011
Soggetti:
Basic and Translational Investigations
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129273/
https://ncbi.nlm.nih.gov/pubmed/21727209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nor050
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