Local delivery of rapamycin: a toxicity and efficacy study in an experimental malignant glioma model in rats

Rapamycin, an anti-proliferative agent, is effective in the treatment of renal cell carcinoma and recurrent breast cancers. We proposed that this potent mammalian target of rapamycin inhibitor may be useful for the treatment of gliomas as well. We examined the cytotoxicity of rapamycin against a rod...

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Detalhes bibliográficos
Main Authors: Tyler, Betty, Wadsworth, Scott, Recinos, Violette, Mehta, Vivek, Vellimana, Ananth, Li, Khan, Rosenblatt, Joel, Do, Hiep, Gallia, Gary L., Siu, I-Mei, Wicks, Robert T., Rudek, Michelle A., Zhao, Ming, Brem, Henry
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Basic and Translational Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129273/
https://ncbi.nlm.nih.gov/pubmed/21727209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nor050
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