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Local delivery of rapamycin: a toxicity and efficacy study in an experimental malignant glioma model in rats

Rapamycin, an anti-proliferative agent, is effective in the treatment of renal cell carcinoma and recurrent breast cancers. We proposed that this potent mammalian target of rapamycin inhibitor may be useful for the treatment of gliomas as well. We examined the cytotoxicity of rapamycin against a rod...

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Bibliografiske detaljer
Main Authors: Tyler, Betty, Wadsworth, Scott, Recinos, Violette, Mehta, Vivek, Vellimana, Ananth, Li, Khan, Rosenblatt, Joel, Do, Hiep, Gallia, Gary L., Siu, I-Mei, Wicks, Robert T., Rudek, Michelle A., Zhao, Ming, Brem, Henry
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129273/
https://ncbi.nlm.nih.gov/pubmed/21727209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nor050
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