Local delivery of cancer-cell glycolytic inhibitors in high-grade glioma

BACKGROUND: 3-bromopyruvate (3-BrPA) and dichloroacetate (DCA) are inhibitors of cancer-cell specific aerobic glycolysis. Their application in glioma is limited by 3-BrPA's inability to cross the blood-brain-barrier and DCA's dose-limiting toxicity. The safety and efficacy of intracranial...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Wicks, Robert T., Azadi, Javad, Mangraviti, Antonella, Zhang, Irma, Hwang, Lee, Joshi, Avadhut, Bow, Hansen, Hutt-Cabezas, Marianne, Martin, Kristin L., Rudek, Michelle A., Zhao, Ming, Brem, Henry, Tyler, Betty M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Basic and Translational Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4483048/
https://ncbi.nlm.nih.gov/pubmed/25053853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou143
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados