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Regulation and Function of the RasGRP Family of Ras Activators in Blood Cells

Ras guanyl nucleotide releasing proteins (RasGRPs) are guanyl nucleotide exchange factors that activate Ras and related GTPases such as Rap. Like Sos proteins, RasGRPs have a catalytic region composed of a Ras exchange motif (REM) and a CDC25 domain. RasGRPs also possess a pair of atypical EF hands...

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Detalhes bibliográficos
Autor principal: Stone, James C.
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3128638/
https://ncbi.nlm.nih.gov/pubmed/21779502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947601911408082
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