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Essential Role for TLR9 in Prime but Not Prime-Boost Plasmid DNA Vaccination To Activate Dendritic Cells and Protect from Lethal Viral Infection

One of the requirements for efficient vaccination against infection is to achieve the best combination of an adequate adjuvant with the antigenic information to deliver. Although plasmid DNA is a promising tool bearing the unique potential to activate humoral and cellular immunity, an actual challen...

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Hlavní autoři: Rottembourg, Diane, Filippi, Christophe M., Bresson, Damien, Ehrhardt, Katrin, Estes, Elizabeth A., Oldham, Janine E., von Herrath, Matthias G.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3128449/
https://ncbi.nlm.nih.gov/pubmed/20483769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0803935
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