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Direct Infection of Dendritic Cells during Chronic Viral Infection Suppresses Antiviral T Cell Proliferation and Induces IL-10 Expression in CD4 T Cells

Elevated levels of systemic IL-10 have been associated with several chronic viral infections, including HCV, EBV, HCMV and LCMV. In the chronic LCMV infection model, both elevated IL-10 and enhanced infection of dendritic cells (DCs) are important for viral persistence. This report highlights the re...

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Bibliografiske detaljer
Main Authors: Baca Jones, Carmen, Filippi, Christophe, Sachithanantham, Sowbarnika, Rodriguez-Calvo, Teresa, Ehrhardt, Katrin, von Herrath, Matthias
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3948950/
https://ncbi.nlm.nih.gov/pubmed/24613988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0090855
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