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Essential Role for TLR9 in Prime but Not Prime-Boost Plasmid DNA Vaccination To Activate Dendritic Cells and Protect from Lethal Viral Infection

One of the requirements for efficient vaccination against infection is to achieve the best combination of an adequate adjuvant with the antigenic information to deliver. Although plasmid DNA is a promising tool bearing the unique potential to activate humoral and cellular immunity, an actual challen...

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Détails bibliographiques
Auteurs principaux: Rottembourg, Diane, Filippi, Christophe M., Bresson, Damien, Ehrhardt, Katrin, Estes, Elizabeth A., Oldham, Janine E., von Herrath, Matthias G.
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3128449/
https://ncbi.nlm.nih.gov/pubmed/20483769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0803935
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