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TLR2 signaling improves immunoregulation to prevent type 1 diabetes

Signaling through Toll-like receptor 2 (TLR2) promotes inflammation and modulates CD4(+)CD25(+) regulatory T cells (Tregs). We assessed mechanistically how this molecule would alter immunoregulation in type 1 diabetes (T1D). We also asked whether TLR2 may be involved in our recent discovery that vir...

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Detalhes bibliográficos
Main Authors: Filippi, Christophe M., Ehrhardt, Katrin, Estes, Elizabeth A., Larsson, Par, Oldham, Janine E., von Herrath, Matthias G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3100206/
https://ncbi.nlm.nih.gov/pubmed/21469083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200939841
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