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Immunoregulatory mechanisms triggered by viral infections protect from type 1 diabetes in mice

Type 1 diabetes (T1D) is an autoimmune disease that is caused by the destruction of insulin-producing β cells. Viral infections induce immune responses that can damage β cells and promote T1D or on the other hand prevent the development of the disease. However, the opposing roles of viral infections...

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Hlavní autoři: Filippi, Christophe M., Estes, Elizabeth A., Oldham, Janine E., von Herrath, Matthias G.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2689128/
https://ncbi.nlm.nih.gov/pubmed/19478458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI38503
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