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Bioelectronic Delivery of Electrons to Cytochrome P450 Enzymes
Cytochrome P450s (cyt P450s) are the major oxidative enzymes in human oxidative metabolism of drugs and xenobiotic chemicals. In nature, the iron heme cyt P450s utilize oxygen and electrons delivered from NADPH by a reductase enzyme to oxidize substrates stereo- and regioselectively. Significant res...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3128182/ https://ncbi.nlm.nih.gov/pubmed/21591685 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp201235m |
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