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Efficient Bioelectronic Actuation of the Natural Catalytic Pathway of Human Metabolic Cytochrome P450s

Cytochrome (cyt) P450s comprise the enzyme superfamily responsible for human oxidative metabolism of a majority of drugs and xenobiotics. Electronic delivery of electrons to cyt P450s could be used to drive the natural catalytic cycle for fundamental investigations, stereo- and regioselective synthe...

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Detalhes bibliográficos
Main Authors: Krishnan, Sadagopan, Wasalathanthri, Dhanuka, Zhao, Linlin, Schenkman, John B., Rusling, James F
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3033457/
https://ncbi.nlm.nih.gov/pubmed/21214177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja108637s
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