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Microfluidic Electrochemical Array for Detection of Reactive Metabolites Formed by Cytochrome P450 Enzymes

A novel, simple, rapid microfluidic array using bioelectronically driven cytochrome P450 enzyme catalysis for reactive metabolite screening is reported for the first time. The device incorporates an 8-electrode screen printed carbon array coated with thin films of DNA, [Ru(bpy)(2)(PVP)(10)](ClO(4))...

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Detalhes bibliográficos
Main Authors: Wasalathanthri, Dhanuka P., Mani, Vigneshwaran, Tang, Chi K., Rusling, James F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3237909/
https://ncbi.nlm.nih.gov/pubmed/22040095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac202269t
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