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Cytochrome P450 Enzyme Metabolites in Lead Discovery and Development

The cytochrome P450 (CYP) enzymes are a versatile superfamily of heme-containing monooxygenases, perhaps best known for their role in the oxidation of xenobiotic compounds. However, due to their unique oxidative chemistry, CYPs are also important in natural product drug discovery and in the generati...

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Dades bibliogràfiques
Publicat a:Annu Rep Med Chem
Autors principals: Kandel, Sylvie E., Wienkers, Larry C., Lampe, Jed N.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4365796/
https://ncbi.nlm.nih.gov/pubmed/25797999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/B978-0-12-800167-7.00022-5
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