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Cytochrome P450 Enzyme Metabolites in Lead Discovery and Development
The cytochrome P450 (CYP) enzymes are a versatile superfamily of heme-containing monooxygenases, perhaps best known for their role in the oxidation of xenobiotic compounds. However, due to their unique oxidative chemistry, CYPs are also important in natural product drug discovery and in the generati...
Gardado en:
| Publicado en: | Annu Rep Med Chem |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4365796/ https://ncbi.nlm.nih.gov/pubmed/25797999 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/B978-0-12-800167-7.00022-5 |
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