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The Neutralization Breadth of HIV-1 Develops Incrementally over Four Years and Is Associated with CD4(+) T Cell Decline and High Viral Load during Acute Infection

An understanding of how broadly neutralizing activity develops in HIV-1-infected individuals is needed to guide vaccine design and immunization strategies. Here we used a large panel of 44 HIV-1 envelope variants (subtypes A, B, and C) to evaluate the presence of broadly neutralizing antibodies in s...

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Main Authors: Gray, Elin S., Madiga, Maphuti C., Hermanus, Tandile, Moore, Penny L., Wibmer, Constantinos Kurt, Tumba, Nancy L., Werner, Lise, Mlisana, Koleka, Sibeko, Sengeziwe, Williamson, Carolyn, Abdool Karim, Salim S., Morris, Lynn
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126191/
https://ncbi.nlm.nih.gov/pubmed/21389135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00198-11
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