Structural Simplification of Bioactive Natural Products with Multicomponent Synthesis. 2. Antiproliferative and Antitubulin Activities of Pyrano[3,2-c]pyridones and Pyrano[3,2-c]quinolones

Pyrano[3,2-c]pyridone and pyrano[3,2-c]quinolone structural motifs are commonly found in alkaloids manifesting diverse biological activities. As part of a program aimed at structural simplification of bioactive natural products utilizing multicomponent synthetic processes, we developed compound libr...

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Detalhes bibliográficos
Main Authors: Magedov, Igor V., Manpadi, Madhuri, Ogasawara, Marcia A., Dhawan, Adriana S., Rogelj, Snezna, Van slambrouck, Severine, Steelant, Wim F. A., Evdokimov, Nikolai M., Uglinskii, Pavel Y., Elias, Eerik M., Knee, Erica J., Tongwa, Paul, Antipin, Mikhail Yu., Kornienko, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3125133/
https://ncbi.nlm.nih.gov/pubmed/18361483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm701499n
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