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Novel Three-Component Synthesis and Antiproliferative Properties of Diversely Functionalized Pyrrolines

Diversely substituted 2–pyrrolines have been prepared by a novel multicomponent process involving a reaction of various N–(aryl– and alkylsulfonamido)–acetophenones with aldehydes and malononitrile. While the reaction is highly regioselective, it is not stereoselective, generating a mixture of cis a...

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Bibliographic Details
Main Authors: Magedov, Igor V., Luchetti, Giovanni, Evdokimov, Nikolai M., Manpadi, Madhuri, Steelant, Wim F. A., Van slambrouck, Severine, Tongwa, Paul, Antipin, Mikhail Yu., Kornienko, Alexander
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3383006/
https://ncbi.nlm.nih.gov/pubmed/18221874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2008.01.019
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