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Role of the WWOX tumor suppressor gene in bone homeostasis and the pathogenesis of osteosarcoma

Osteosarcoma is the most common primary bone malignancy in children with unknown etiology and often with poor clinical outcome. In recent years, a critical role has emerged for the WW domain-containing oxidoreductase (WWOX) in osteosarcoma and bone biology. WWOX is a tumor suppressor that is deleted...

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Bibliografske podrobnosti
Main Authors: Del Mare, Sara, Kurek, Kyle C, Stein, Gary S, Lian, Jane B, Aqeilan, Rami I
Format: Artigo
Jezik:Inglês
Izdano: e-Century Publishing Corporation 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3124638/
https://ncbi.nlm.nih.gov/pubmed/21731849
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