Conditional inactivation of the mouse Wwox tumor suppressor gene recapitulates the null phenotype()

WW domain-containing oxidoreductase (WWOX) is highly conserved in both humans and murine. WWOX spans the second most common human chromosomal fragile site, FRA16D, and is commonly inactivated in multiple human cancers. Modeling WWOX inactivation in mice revealed a complex phenotype including postnat...

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Bibliografiska uppgifter
Huvudupphovsmän: Abdeen, Suhaib K., Mare, Sara Del, Hussain, Sadeeq, Remaileh, Muhannad Abu, Salah, Zaidoun, Hagan, John, Rawahneh, Maysoon, Pu, Xin-an, Russell, Stacey, Stein, Janet L., Stein, Gary S., Lian, Jane B., Aqeilan, Rami I.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2013
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3943428/
https://ncbi.nlm.nih.gov/pubmed/23254685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.24308
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