Conditional inactivation of the mouse Wwox tumor suppressor gene recapitulates the null phenotype()

WW domain-containing oxidoreductase (WWOX) is highly conserved in both humans and murine. WWOX spans the second most common human chromosomal fragile site, FRA16D, and is commonly inactivated in multiple human cancers. Modeling WWOX inactivation in mice revealed a complex phenotype including postnat...

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Detaylı Bibliyografya
Asıl Yazarlar: Abdeen, Suhaib K., Mare, Sara Del, Hussain, Sadeeq, Remaileh, Muhannad Abu, Salah, Zaidoun, Hagan, John, Rawahneh, Maysoon, Pu, Xin-an, Russell, Stacey, Stein, Janet L., Stein, Gary S., Lian, Jane B., Aqeilan, Rami I.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3943428/
https://ncbi.nlm.nih.gov/pubmed/23254685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.24308
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