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Conditional inactivation of the mouse Wwox tumor suppressor gene recapitulates the null phenotype()
WW domain-containing oxidoreductase (WWOX) is highly conserved in both humans and murine. WWOX spans the second most common human chromosomal fragile site, FRA16D, and is commonly inactivated in multiple human cancers. Modeling WWOX inactivation in mice revealed a complex phenotype including postnat...
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| Asıl Yazarlar: | , , , , , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2013
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3943428/ https://ncbi.nlm.nih.gov/pubmed/23254685 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.24308 |
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