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WWOX and p53 Dysregulation Synergize to Drive the Development of Osteosarcoma

Osteosarcoma (OS) is a highly metastatic form of bone cancer in adolescents and young adults which is resistant to existing treatments. Development of an effective therapy has been hindered by very limited understanding of the mechanisms of osteosarcomagenesis. Here, we used genetically engineered m...

詳細記述

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書誌詳細
出版年:Cancer Res
主要な著者: Del Mare, Sara, Husanie, Hussam, Iancu, Ortal, Abu-Odeh, Mohammad, Evangelou, Konstantinos, Lovat, Francesca, Volinia, Stefano, Gordon, Jonathan, Amir, Gail, Stein, Janet, Stein, Gary S., Croce, Carlo M., Gorgoulis, Vassilis, Lian, Jane B., Aqeilan, Rami I.
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5146760/
https://ncbi.nlm.nih.gov/pubmed/27550453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-16-0621
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