DNA sequence selectivity of guanine-N7 alkylation by nitrogen mustards is preserved in intact cells.
Nitrogen mustard alkylating agents react with isolated DNA in a sequence selective manner, and the substituent attached to the drug reactive group can impose a distinct sequence preference. It is not clear however to what extent the observed DNA sequence preferences are preserved in intact cells. Th...
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| Опубликовано в:: | Nucleic Acids Res |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
1992
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| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC312455/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1620613/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/20.12.3175 |
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