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DNA sequence selectivity of guanine-N7 alkylation by nitrogen mustards is preserved in intact cells.
Nitrogen mustard alkylating agents react with isolated DNA in a sequence selective manner, and the substituent attached to the drug reactive group can impose a distinct sequence preference. It is not clear however to what extent the observed DNA sequence preferences are preserved in intact cells. Th...
Tallennettuna:
| Päätekijät: | , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
1992
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| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC312455/ https://ncbi.nlm.nih.gov/pubmed/1620613 |
| Tagit: |
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