nNOS Inhibition Improves Diastolic Function and Reduces Oxidative Stress in Ovariectomized-mRen2.Lewis Rats

OBJECTIVE: The loss of estrogen in mRen2.Lewis rats leads to an exacerbation of diastolic dysfunction. Since specific neuronal nitric oxide synthase inhibition reverses renal damage in the same model, we assessed the effects of inhibiting neuronal nitric oxide on diastolic function, left ventricular...

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Auteurs principaux: Jessup, Jewell A., Zhang, Lili, Chen, Alex F., Presley, Tennille D., Kim-Shapiro, Daniel B., Chappell, Mark, Wang, Hao, Groban, Leanne
Format: Artigo
Langue:Inglês
Publié: 2011
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3123430/
https://ncbi.nlm.nih.gov/pubmed/21293310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/gme.0b013e31820390a2
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