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Estrogen Therapy, Independent of Timing, Improves Cardiac Structure and Function in Oophorectomized mRen2.Lewis Rats

OBJECTIVE: mRen2.Lewis Rats exhibit exacerbated increases in blood pressure, left ventricular (LV) remodeling, and diastolic impairment following the loss of estrogens. In this same model, depletion of estrogens has marked effects on the cardiac biopterin profile concomitant with suppressed nitric o...

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Detalhes bibliográficos
Main Authors: Jessup, Jewell A., Wang, Hao, MacNamara, Lindsay M., Presley, Tennille D., Kim-Shapiro, Daniel B., Zhang, Lili, Chen, Alex F., Groban, Leanne
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3690139/
https://ncbi.nlm.nih.gov/pubmed/23481117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/GME.0b013e318280589a
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