Estrogen Therapy, Independent of Timing, Improves Cardiac Structure and Function in Oophorectomized mRen2.Lewis Rats

OBJECTIVE: mRen2.Lewis Rats exhibit exacerbated increases in blood pressure, left ventricular (LV) remodeling, and diastolic impairment following the loss of estrogens. In this same model, depletion of estrogens has marked effects on the cardiac biopterin profile concomitant with suppressed nitric o...

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Hauptverfasser: Jessup, Jewell A., Wang, Hao, MacNamara, Lindsay M., Presley, Tennille D., Kim-Shapiro, Daniel B., Zhang, Lili, Chen, Alex F., Groban, Leanne
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3690139/
https://ncbi.nlm.nih.gov/pubmed/23481117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/GME.0b013e318280589a
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