Dual ACE-inhibition and AT(1) Receptor Antagonism Improves Ventricular Lusitropy without Affecting Cardiac Fibrosis in the Congenic mRen2.Lewis Rat

PURPOSE: Hypertension and left ventricular (LV) hypertrophy often precede diastolic dysfunction and are risk factors for diastolic heart failure. Although pharmacologic inhibition of the renin angiotensin system (RAS) improves diastolic function and functional capacity in hypertensive patients with...

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Autors principals: Jessup, Jewell A., Westwood, Brian M., Chappell, Mark C., Groban, Leanne
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825563/
https://ncbi.nlm.nih.gov/pubmed/19531557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1753944709338489
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