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Dual ACE-inhibition and AT(1) Receptor Antagonism Improves Ventricular Lusitropy without Affecting Cardiac Fibrosis in the Congenic mRen2.Lewis Rat

PURPOSE: Hypertension and left ventricular (LV) hypertrophy often precede diastolic dysfunction and are risk factors for diastolic heart failure. Although pharmacologic inhibition of the renin angiotensin system (RAS) improves diastolic function and functional capacity in hypertensive patients with...

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Detalhes bibliográficos
Main Authors: Jessup, Jewell A., Westwood, Brian M., Chappell, Mark C., Groban, Leanne
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825563/
https://ncbi.nlm.nih.gov/pubmed/19531557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1753944709338489
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