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nNOS Inhibition Improves Diastolic Function and Reduces Oxidative Stress in Ovariectomized-mRen2.Lewis Rats

OBJECTIVE: The loss of estrogen in mRen2.Lewis rats leads to an exacerbation of diastolic dysfunction. Since specific neuronal nitric oxide synthase inhibition reverses renal damage in the same model, we assessed the effects of inhibiting neuronal nitric oxide on diastolic function, left ventricular...

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Detalhes bibliográficos
Main Authors: Jessup, Jewell A., Zhang, Lili, Chen, Alex F., Presley, Tennille D., Kim-Shapiro, Daniel B., Chappell, Mark, Wang, Hao, Groban, Leanne
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3123430/
https://ncbi.nlm.nih.gov/pubmed/21293310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/gme.0b013e31820390a2
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