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The importance of RT-qPCR primer design for the detection of siRNA-mediated mRNA silencing

BACKGROUND: The use of RNAi to analyse gene function in vitro is now widely applied in biological research. However, several difficulties are associated with its use in vivo, mainly relating to inefficient delivery and non-specific effects of short RNA duplexes in animal models. The latter can lead...

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Hlavní autoři: Herbert, Mike, Coppieters, Natacha, Lasham, Annette, Cao, Helen, Reid, Glen
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3123217/
https://ncbi.nlm.nih.gov/pubmed/21612654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-4-148
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