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Active Site-labeled Prothrombin Inhibits Prothrombinase in Vitro and Thrombosis in Vivo
Mouse and human prothrombin (ProT) active site specifically labeled with d-Phe-Pro-Arg-CH(2)Cl (FPR-ProT) inhibited tissue factor-initiated thrombin generation in platelet-rich and platelet-poor mouse and human plasmas. FPR-prethrombin 1 (Pre 1), fragment 1 (F1), fragment 1.2 (F1.2), and FPR-thrombi...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3123099/ https://ncbi.nlm.nih.gov/pubmed/21531712 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.230292 |
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