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α-Synuclein Populates Both Elongated and Broken Helix States on Small Unilamellar Vesicles
The misfolding of the protein α-synuclein (αS) has been implicated in the molecular chain of events leading to Parkinson disease. Physiologically, αS undergoes a transition from a random coil to helical conformation upon encountering synaptic vesicle membranes. On analogous small unilamellar vesicle...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3122204/ https://ncbi.nlm.nih.gov/pubmed/21524999 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.224055 |
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