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α-Synuclein binds large unilamellar vesicles as an extended helix

Interactions between the synaptic protein α-Synuclein and cellular membranes may be relevant both to its native function as well as its role in Parkinson’s disease. We use single molecule Förster resonance energy transfer to probe the structure of α-Synuclein bound to detergent micelles and lipid ve...

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Detalhes bibliográficos
Main Authors: Trexler, Adam J., Rhoades, Elizabeth
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2837115/
https://ncbi.nlm.nih.gov/pubmed/19220042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi900114z
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