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Single Molecule Characterization of α-Synuclein in Aggregation-Prone States

α-Synuclein (αS) is an intrinsically disordered protein whose aggregation into ordered, fibrillar structures underlies the pathogenesis of Parkinson's disease. A full understanding of the factors that cause its conversion from soluble protein to insoluble aggregate requires characterization of...

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Bibliografski detalji
Glavni autori: Trexler, Adam J., Rhoades, Elizabeth
Format: Artigo
Jezik:Inglês
Izdano: The Biophysical Society 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2965999/
https://ncbi.nlm.nih.gov/pubmed/21044603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.08.056
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