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Single Molecule Characterization of α-Synuclein in Aggregation-Prone States
α-Synuclein (αS) is an intrinsically disordered protein whose aggregation into ordered, fibrillar structures underlies the pathogenesis of Parkinson's disease. A full understanding of the factors that cause its conversion from soluble protein to insoluble aggregate requires characterization of...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2965999/ https://ncbi.nlm.nih.gov/pubmed/21044603 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.08.056 |
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