The Conformational Ensembles of α-Synuclein and Tau: Combining Single-Molecule FRET and Simulations

Intrinsically disordered proteins (IDPs) are increasingly recognized for their important roles in a range of biological contexts, both in normal physiological function and in a variety of devastating human diseases. However, their structural characterization by traditional biophysical methods, for t...

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Detalhes bibliográficos
Main Authors: Nath, Abhinav, Sammalkorpi, Maria, DeWitt, David C., Trexler, Adam J., Elbaum-Garfinkle, Shana, O’Hern, Corey S., Rhoades, Elizabeth
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2012
Assuntos:
Proteins and Nucleic Acids
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3491709/
https://ncbi.nlm.nih.gov/pubmed/23199922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.09.032
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