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Identification of an aggregation-prone structure of tau
The aggregation and deposition of normally soluble proteins is the hallmark of several devastating neurodegenerative disorders. For proteins such as tau in Alzheimer’s disease and α-synuclein in Parkinson’s disease, aggregation involves a transition from an intrinsically disordered monomer to a high...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3477793/ https://ncbi.nlm.nih.gov/pubmed/22998648 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja305206m |
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