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A functional role for intrinsic disorder in the tau-tubulin complex
Tau is an intrinsically disordered protein with an important role in maintaining the dynamic instability of neuronal microtubules. Despite intensive study, a detailed understanding of the functional mechanism of tau is lacking. Here, we address this deficiency by using intramolecular single-molecule...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5167143/ https://ncbi.nlm.nih.gov/pubmed/27911791 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1610137113 |
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