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Effects of Curvature and Composition on α-Synuclein Binding to Lipid Vesicles

Parkinson's disease is characterized by the presence of intracellular aggregates composed primarily of the neuronal protein α-synuclein (αS). Interactions between αS and various cellular membranes are thought to be important to its native function as well as relevant to its role in disease. We...

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Hlavní autoři: Middleton, Elizabeth R., Rhoades, Elizabeth
Médium: Artigo
Jazyk:Inglês
Vydáno: The Biophysical Society 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3042580/
https://ncbi.nlm.nih.gov/pubmed/20923663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.07.056
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