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Quantification of α-Synuclein Binding to Lipid Vesicles Using Fluorescence Correlation Spectroscopy

α-Synuclein (αS) is a soluble synaptic protein that is the major proteinaceous component of insoluble fibrillar Lewy body deposits that are the hallmark of Parkinson's disease. The interaction of αS with synaptic vesicles is thought to be critical both to its normal function as well as to its p...

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Detalhes bibliográficos
Main Authors: Rhoades, Elizabeth, Ramlall, Trudy F., Webb, Watt W., Eliezer, David
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1471845/
https://ncbi.nlm.nih.gov/pubmed/16581836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.079251
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