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Quantification of α-Synuclein Binding to Lipid Vesicles Using Fluorescence Correlation Spectroscopy

α-Synuclein (αS) is a soluble synaptic protein that is the major proteinaceous component of insoluble fibrillar Lewy body deposits that are the hallmark of Parkinson's disease. The interaction of αS with synaptic vesicles is thought to be critical both to its normal function as well as to its p...

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Hlavní autoři: Rhoades, Elizabeth, Ramlall, Trudy F., Webb, Watt W., Eliezer, David
Médium: Artigo
Jazyk:Inglês
Vydáno: Biophysical Society 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1471845/
https://ncbi.nlm.nih.gov/pubmed/16581836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.079251
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